Role of mTORC1 signalling in intracellular processing and trafficking of Alzheimer’s disease associated amyloid precursor protein and its derivatives
mTORC1 is a key intracellular signalling component with a proposed role in Alzheimer disease. The project is focused on the link between mTORC1 and β-amyloid processing in neuronal cells. Molecular processes are investigated directly in cells using fluorescence techniques, including super-resolution microscopy available in the laboratory.
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